Exploring Environmental and Lifestyle Factors in Alzheimers Disease Risk
Introduction
Alzheimers is a disease that is only growing with casualties as humans live longer and give Alzheimers a chance to take over the brain. The United States culture has been very active in letting people know what causes other diseases like cancer and heart attacks. Yet, it is seemingly talked about what causes Alzheimers. Most Americans believe that it is an inherited disease, and thats the only way a person can get it. But in reality, only 30 to 40 percent of Alzheimers victims get it generically; the rest get infected by (environmental).
Some of the many ways a person can get Alzheimers are easy things like having stress, not getting quality sleep, having a bad diet, not taking care of the brain, and changing it to keep it healthy. All of these causes are due to not living a healthy lifestyle. By living a healthier lifestyle and being aware and educated about the possible ways to get Alzheimers, people should have a better chance of never getting the horrendous disease that tears away memories, happiness, and sole, and the percentage of Alzheimers victims should go down from the sixth leading cause of death in America, instead of going up.
Unmasking Alzheimers Causality
There is beginning to be a link between environmental exposure and Alzheimers. There is a very strong connection already found by scientists that pesticides DDT can cause Parkinsons disease. There is beginning to be a study correlation between DDT and Alzheimers. Dr. Jason Richards at Rutgers University did a study that tested the blood of people who had Alzheimers. They tested the blood for DDT and DDE in most of the pertisapents, and they had levels of DDT and DDE four times greater than the control group. (Sneed) There is no surgeon answer as to how DDT and DDE can cause Alzhiermsers, but Dr. Jason Richards believes, But he speculates that DDT/DDE somehow encourage growth of the amyloid proteins that make up the plaques associated with the disease. (Sneed)
Sleep, Stress, and Cognitive Health
In life, humans develop diseases, and a lot of these diseases are caused by some sort of unhealthy lifestyle. It is very common for one disease to lead to another. In the case of Alzheimers, studies are showing that people who already have high cholesterol, elevated blood pressure, and diabetes have a greater chance of getting Alzheimers disease. (Reuters Health) Dr. Rebecca Gottesman of Johns Hopkins University School of Medicine said, Each alone may not be enough to increase the risk of Alzheimers disease, but having a number of these risk factors appears to be associated with an even higher risk (Reuters Health) of getting Alzheimers disease.
This does not prove that if a person has one of these diseases, he or she will doomingly have Alzheimers, too. This does support that vascular risk factors might directly impact Alzheimers changes in the brain (Reuters Health). If vascular risk factors do impact getting Alzheimers, then it would be good for those individuals to know that they have a high risk of getting Alzheimers. After knowing that they can have time to do anything they can to delay or eliminate the disease. Not a lot of Americans have any idea that high cholesterol, elevated blood pressure, and diabetes could lead to Alzheimers disease. High cholesterol, elevated blood pressure, and diabetes are very common illnesses in America, and yet there is very little talk about how they can cause Alzheimers disease.
Stress and sleep are two things that Americans do all the time, and they have no idea that it can affect their mental health. Poor sleep can lead to high levels of beta-amyloid. Beta-amyloid is a brain-clogging protein. The brain tries to activate mechanisms to try to repair the myelin. The beta-amyloid blocks the repair mechanisms, and the brain stops producing myelin. Uninterrupted deep sleep is very important to the brain by helping flush the brain toxic out of the brain.
Persistent Stress and Chronic stress can hinder nerve cell growth and shrinkage in the memory area tissue of the brain. Hindering nerve cell growth leads to Alzheimers by the death of nerve cells. Alzheimers kills nervous cells, and if the nerve cells are prohibited from growing, this will increase the chance of getting Alzheimers, which could be caused by Persistent Stress and Chronic stress. The shrinkage of the memory tissue of the brain can lead to Alzheimers. The most common way Dementia starts is with the shrinkage of the brain tissue. Alzheimers is the most common form of Dementia. When the memory tissues start to shrink, the brain starts to forget memories. The most common forgotten memory of early memory tissue shrinkage is recent/newer memories. Need a source for this one.
Unhealthy diets can increase a persons chance of getting Alzheimers by causing inflammation and insulin resistance in the brain, which injure neurons and inhibit communication between brain cells. An unhealthy diet leads to metabolic disorder, which is linked to the signal-processing system in the brain. Eating excessively processed foods can, along with other fatty foods, create insulin resistance, which will injure neurons in the brain. Refine carbs can make the brain have dramatic shifts in blood sugar, which can lead to insulin resistance; not eating a good helping of omega-three fat foods will not help the brain and could lead to Alzheimers because omega-three fat foods have beta-amyloid plaques, which will help prevent Alzheimers (Mace) pg:334.
Not taking the right vitamins could also lead to Alzheimers. Folic acid, vitamin B2, vitamin D, magnesium, fish oil, vitamin E, ginkgo biloba, and coenzyme Q0 help preserve the brain and decrease inflammation in the brain. Douud, Gwenale Preventing Alzhimers Dieses-Related to Gray Matter by Vitamin B Treatment says that use of vitamin B intake supplements have reduced as much as seven-folds, cerebral atrophy in the gray matter Pp 9523-9528; The effect that the vitamin B supplement possibly affects grey matter to support the brain health and prevent Alzheimers. Not taking the right vitamins could affect the chances of a person getting Alzheimers. The 36-Hour Day, by Mace, Nancy L., and Peter V. Rabins, explains how Having a poor diet can lead to Cognitive Decline.
Cognit
ive Engagement and Social Interaction
Cognitive abilities are memory and thinking skills. A person who has a cognitive decline has a very high risk factor of getting Alzheimers. Nitrosamines are nitrogen-based fertilizers that are used in Tabaco products, color, flavor, and preserve natural foods (Sneed). Researcher Suzanne de la Monte of Brown Universitys Warren Alpert Medical School believes there is a connection between the rising number of Alzheimers cases and the greater amounts of nitrogen-based chemicals added to our food (Sneed). America has consumed extranmical amounts of tobacco, food color, flavor, and preserved foods. If the link between nitrosamines and causing Alzheimers is true, then America should be worried and start to avoid those products.
Living a physically active life could cause and lead to Alzheimers. The Alzheimers Research & Prevention Foundation said physical exercise can reduce a persons risk of developing Alzheimers by up to 50 percent. By not participating in physical activity, an individual does not stimulate the brain, which provides its ability to make and maintain connections in the brain. Not being able to make and maintain old connections in the brain can lead to the deterioration of neurons in the brain and ultimately start Alzheimers.
Naftolin, Frederick, and Mitchell Harmanss scholarly journal Preventing Alzheimers Disease and Cognitive decline describes The interaction between physical activity and the putative mechanisms underlying Alzheimers disease progression. (Putative mechanisms, means the cause of death.) Naftolin, Frederick, and Mitchell Harmans research that if a person is not physically active, it can lead to putative mechanisms of Alzheimers. When a person is physically active, they should avoid letting their head get hit and causing a head injury. Head injuries can increase a persons chance of getting Alzheimers and is a greater chance after the age of fifty-five.
Physical Activity and Brain Vitality
Like most diseases, there are many contributing factors to getting Alzheimers. Brain health is a very important thing, and it is what Alzheimers attacks and breaks down. Not having a healthy working brain can lead to Alzheimers. There are many different ways that the brain can deteriorate and lead to Alzheimers.
Keeping the brain working is a way to prevent Alzheimers. A person that is not socially active and doesnt have conversations with other human beings could lead to the deterioration of the brain and ultimately lead to Alzheimers. Not keeping the brain active and not challenging it daily could lead to Alzheimers. An example of keeping the brain actively thinking would be doing crossword puzzles, reading, brain food learning tools, and games.
When people dont practice their memory, examples like looking at old photo albums and working on attaining a great memory could be in danger of Alzheimers. A Study conducted by NIH ACTIVE Help Guide said, Older adults who received as few as ten sessions of mental training not only improved their cognitive functioning in daily activities in the months after the training but continued to show long-lasting improvements ten years later. The NIH ACTIVE study provides evidence that not doing anything to help the brains health will not help it continue to be healthy and could lead to the deterioration of the brain.
Alzheimers can be passed down genetically. 30 to 40 percent of Alzheimers is passed down genetically. Alzheimers can be passed down genetically by getting an APOE gene from one of your parents. Not everyone who has an APOE gene gets Alzheimers. The common miss belief is that Alzheimers is a genetic gene; if a person in the family has Alzheimers, the individuals in that family will get the disease. This is false because 30 to 40 percent of Alzheimers victims get the disease through a genetic trait; the rest are (Environmental and lifestyle).
Pesticides and Environmental Exposure
Environmental, Lifestyle Alzheimers can mean that humans get diseases through environmental factors and exposure. It can also mean that the diseases were gotten through lifestyle. Lifestyle is the way you live your life and what you do to cause or prevent Alzheimers. A study done by the British Medical Journal claimed that Missense mutations in three genes are known to cause atonal dominant forms of early onset Alzheimers diseases.
The amyloid precursor protein gene is located on chromosome 2, and genes for presenilin one and presenilin two are located on chromosome 4 and . These are the different genes that the Alzheimers trait can be passed down on. The British Health Article did a survey, and they decided that the 50 or so mutations associated with presenilin one may explain up to half of all cases of early-onset Alzheimers disease. Half of the early cases of Alzheimers of the mutations associated with Presenilin conflicts with the theory that only 30 to 40 percent of Alzheimers victims get it through genetics.
Conclusion
Alzheimers disease occurs when brain cells and their connections degenerate and die, which leads to confusion and memory loss. Over 5.5 million Americans have Alzheimers Disease, and there is a 0 percent chance of getting it after turning 65 years old. Alzheimers is the sixth leading cause of death in America. Yet in America, we are not as worried about the causes of Alzheimers compared to our concern with other diseases, such as cancer.
However, Alzheimers Disease is one of the more horrible ways to die, and there needs to be a greater awareness of what causes it to aid in reducing a persons chances of falling victim to this horrible, deadly disease. Most Americans are educated on what can cause/increase the risk of common diseases such as cancer. However, the causes or risk factors of Alzheimers Disease are seldom talked about. People need to be educated and aware of the factors that can increase a persons chances of
getting the horrendous brain-deadening disease, Alzheimers.
References
Still Alice by Lisa Genova
The Forgetting: Alzheimers: Portrait of an Epidemic by David Shenk
On Pluto: Inside the Mind of Alzheimers by Greg OBrien
Creating Moments of Joy Along the Alzheimers Journey: A Guide for Families and Caregivers by Jolene Brackey
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